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Updated: Sep 19, 2025

Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation
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Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation

Published on: February 28, 2019

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膜结合的IL-15共同表达有助于强大而持久的CD70向的TRuC T细胞疗法

Lindsay Webb1, Michael Lofgren2, Troy Patterson1

  • 1TCR2 Therapeutics, Inc., Cambridge, MA, United States.

Frontiers in immunology
|June 16, 2025
PubMed
概括

这项研究介绍了ADP-520,一种针对CD70的新型T细胞疗法,用于固体瘤. 增强了IL-15,它显示出强大的抗瘤活性和改善的T细胞持久性,提供了一个有前途的新免疫疗法选择.

关键词:
CD7070 CD7070 CD7070 CD7070 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70 CD70它们的IL-15型.T细胞免疫疗法免疫疗法TRuC T 细胞治疗杀害兄弟的抵抗力强.持续性 持久性细胞癌瘤是细胞癌.固体瘤是一个固体瘤.

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Generation of Multivirus-specific T Cells to Prevent/treat Viral Infections after Allogeneic Hematopoietic Stem Cell Transplant08:52

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