与过敏相关的皮肤疾病:从1990年到2021年的全球疾病负担以及未来的趋势
Xiao Tang1, Li Lin1, Fangning Yu1
1Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China.
The World Allergy Organization journal
|June 16, 2025
概括
全球范围内,像阿托皮性皮肤炎 (AD) 这样的过敏性皮肤疾病正在增加. 虽然阿尔茨海默病的发病率正在下降,但接触性皮炎 (CD) 和疹需要更多的关注和研究.
科学领域:
- 皮肤病学 皮肤病学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 过敏性皮肤疾病,包括阿托皮性皮肤炎 (AD),疹和接触性皮肤炎 (CD),代表着重大的全球健康挑战.
- 目前还没有对这些条件的全球负担进行全面的系统分析.
研究的目的:
- 量化AD,CD和疹的全球负担.
- 评估这些过敏性皮肤疾病的全球流行病学模式.
- 用贝叶斯年龄-周期-队列 (BAPC) 模型预测未来的疾病负担.
主要方法:
- 利用全球疾病负担 (GBD) 数据库评估发病率,流行率和DALYs.
- 采用贝叶斯年龄-周期-队列 (BAPC) 模型进行15年疾病负担预测.
- 分析了从1990年到2021年的趋势,包括年龄标准化流行率 (ASPR) 和与社会人口指数 (SDI) 的相关性.
主要成果:
- 从1990年到2021年,AD,CD和疹的全球病例增加了.
- 在2021年,阿尔茨海默病的患病率达到1.29亿,但其ASPR却下降了 (-0.28).
- 结核病的发病率最高 (2021年为2.53亿例);结核病和疹在生命早期达到顶峰,而结核病在晚年 (75-79岁) 达到顶峰.
- AD与SDI有很强的正相关性 (ρ = 0.626);在高SDI地区,这三个条件都下降了.
结论:
- 全球过敏性皮肤疾病的总体疾病负担正在增加.
- 阿尔茨海默病的年龄标准化率正在下降,预计将进一步下降.
- 接触性皮炎和疹需要更多的公共卫生关注,因为它们的负担越来越大.
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