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Updated: Sep 19, 2025

Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells
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Published on: February 21, 2018

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HGF/c-MET轴通过调节多种机制,有助于CLL细胞存活,使其成为CLL治疗的潜在治疗点

Shihao Liang1, Xiaoya Shao2, Xueqiong Meng3,4,5

  • 1Henan International Joint Laboratory of Thrombosis and Hemostasis, School of Basic Medical Sciences, Henan University of Science and Technology, Luoyang, China.

Frontiers in pharmacology
|June 16, 2025
PubMed
概括

肝细胞生长因子 (HGF) 通过激活亲生存途径,促进慢性淋巴细胞白血病 (CLL) 细胞存活. 用capmatinib准HGF/c-MET通路抑制了CLL生长并增强了细胞亡,提供了潜在的新治疗策略.

关键词:
在HGF/c-Met中使用.抗亡蛋白质是一种抗亡蛋白质.卡普马提尼布 (capmatinib) 是一种药物.慢性淋巴细胞白血病 慢性淋巴细胞白血病信号通道的信号通道.

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