淋巴细胞疾病病理诊断中的陷:为什么要停留在一个?
1Department of Pathology, Duke University Medical Center, Durham, NC, USA.
Glomerular diseases
|June 16, 2025
概括
在活检中识别多种病理是具有挑战性的. 识别不同异常之间的关系并避免诊断陷对于准确诊断至关重要.
科学领域:
- 腎病理學 腎病理學
- 脏病理学 脏病理学
- 诊断方面的挑战
背景情况:
- 评估脏活检存在挑战,特别是多种病理过程的存在.
- 了解并发脏异常之间的相互关系可能是复杂的.
- 对于没有准备的病理学家来说,诊断陷可能会出现.
研究的目的:
- 检查多种病理过程中评估脏活检所面临的挑战和陷.
- 为了说明同时发生的病变之间的各种关系.
- 强调病理学中彻底分析的重要性.
主要方法:
- 综述了30多年来一个单一的病理学实践中的病例.
- 在活检中发现的多种病理过程之间的相互关系的分析.
- 检查在活检评估中遇到的诊断陷.
主要成果:
- 活检中的多种病理过程可以以各种方式联系在一起:单一的原因,后果,与治疗有关的,间接的或偶然的.
- 无法识别第二次病变可能源于过度聚焦,微妙,不寻常的呈现,模糊或子集发现.
- 来自长期实践的插图突出了常见和不常见的场景.
结论:
- 准确的诊断需要使用所有诊断方法,并彻底检查所有组织.
- 需要仔细注意临床记录,承认潜在的不准确性.
- 病理学家必须避免过早关闭,即使在确定初始异常后,也必须继续分析.
相关概念视频
Renal Corpuscle
3.4K
The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
3.4K
Nephrons
3.5K
The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma...
3.5K
Nephrotic Syndrome I : Introduction
37
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
37
Chronic Kidney Disease I: Introduction
78
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
78
Acute Kidney Injury II: Pathophysiology
101
Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
101
Nephrotic Syndrome II : Assessment and Medical Management
26
IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
26


