在接受维护血液透析的患者中,TyG指数对缺血性中风的预测值
Yaqing Wang1, Xiaojie He2, Yuqing Wang2
1Graduate School of Chengde Medical University, Chengde, Hebei, China.
Frontiers in medicine
|June 16, 2025
概括
在维护血液透析患者中,甘油三糖 (TyG) 指数较高,这些患者经历了新发作的缺血性中风 (IS). 较高的TyG指数可以预测该人群中的IS风险.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 神经学 神经学
- 代谢综合征是代谢综合征的一种.
背景情况:
- 甘油三糖指数 (TyG) 是胰岛素抵抗 (IR) 的标志物.
- 之前的研究将TyG指数与脑血管疾病联系起来.
- 维护血液透析 (MHD) 患者新发性缺血性中风 (IS) 的TyG指数的预测值尚未得到充分确立.
研究的目的:
- 调查TyG指数与MHD患者中IS发生的相关性.
- 评估TyG指数作为MHD患者新发性IS的潜在预测指标.
主要方法:
- 从MHD患者 (2019年1月至2024年1月) 分析临床数据和部CT结果.
- 使用空腹血糖和甘油三水平计算TyG指数.
- 后勤回归和ROC曲线分析,以评估对IS的TyG指数的关联性和预测值.
主要成果:
- 与没有IS的患者相比,MHD患者的TyG指数值显著更高 (9.32与8.59,P<0.001).
- 在MHD患者中,提升的TyG指数与IS独立相关 (OR = 2.09,P < 0.001).
- ROC分析表明,在MHD患者中预测IS的最佳TyG指数截止值为9.2 (AUC = 0.75,P < 0.001).
结论:
- 在MHD患者中,新发性IS患者的甘油三指数显著升高.
- 泰格指数作为潜在的风险因素,并为MHD患者的IS提供临床诊断价值.
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