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2020年至2022年在泰国环境水域中对人类口腔病毒的分子检测和表征

Kattareeya Kumthip^1,2, Pattara Khamrin^1,2, Arpaporn Yodmeeklin^1,2

¹Department of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.

One health (Amsterdam, Netherlands)

|June 16, 2025

概括

人类口腔病毒 (HBoV) 在泰国5.3%的水样中被发现,废水污染率最高. 这表明潜在的水传播传播,并强调需要持续的环境监测.

科学领域:

环境微生物学环境微生物学
病毒学病毒学
公共卫生公共卫生

背景情况:

人类口腔病毒 (HBoV) 是已知的儿童呼吸道和胃肠道疾病的原因之一.
在水中检测到HBoV引发了对潜在的水中传播途径的担忧.

研究的目的:

在泰国清迈的环境水源中确定HBoV的流行率和遗传多样性.
在COVID-19大流行期间评估HBoV污染水平和基因型.

主要方法:

使用聚合酶链反应 (PCR) 分析了600个环境水样.
核酸测序和遗传学分析以确定HBoV基因型.
从2020年7月到2022年12月收集数据.

主要成果:

在5.3%的样本中检测到HBoV,废水显示最高率 (23.3%).
确定了所有四种已知的基因型 (HBoV1-HBoV4),其中HBoV2是最常见的 (59.4%).
在COVID-19大流行期间,发现率下降.

结论:

泰国的环境水源拥有多种HBoV基因型,废水是重要的水库.
基因分析表明可能的人类-环境HBoV传播.
持续监测对于了解HBoV的环境动态和公共卫生风险至关重要.

关键词:

环境水环境水基因型基因型基因型人口口腔病毒人类口腔病毒泰国泰国泰国泰国通过水传播的传播.

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