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Updated: Jul 6, 2026

In Vivo Electrophysiological Measurement of Compound Muscle Action Potential from the Forelimbs in Mouse Models of Motor Neuron Degeneration
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MYNAH Registry:一种新的方法来解码退行性宫骨髓病变的自然史

Nashwa Najib1,2,3, Alisha W Sial1,2,3, Hussain Bohra1,2

  • 1Spine Labs & Spine Service, Department of Orthopaedic Surgery, Discipline of Surgery, St George Hospital, Sydney, Australia.

Journal of clinical orthopaedics and trauma
|June 16, 2025
PubMed
概括

这项研究研究了环境因素对细胞过程的影响. 我们的研究结果表明,污染物暴露和模型生物的基因表达改变之间存在显著的相关性.

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Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...