女孩的卵巢体积被认为是过早的青春期
Onder Durmaz1, Erdem Fatihoglu1, Berna Hatun Ozkan1
1Department of Radiology, Faculty of Medicine, Erzincan Binali Yildirim University, Erzincan, Turkey.
Journal of medical ultrasound
|June 16, 2025
概括
女孩早期的青春期 (PP) 与卵巢体积增加和骨老化有关. 较高的卵巢体积预测PP,较大的体积表明更多的症状.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 生殖健康 生殖健康
- 医疗成像医学成像
背景情况:
- 同性性早熟青春期 (PP) 被定义为女孩8岁和男孩9岁之前出现的二次性特征.
- 早期青春期可以对儿童产生显著的身体和心理影响.
- 了解PP的早期指标对于及时诊断和管理至关重要.
研究的目的:
- 为了评估卵巢体积和骨年龄测量与早期青春期诊断的女性患者的症状数量之间的关联.
- 为了确定卵巢体积是否可以预测早期青春期症状的存在和严重程度.
主要方法:
- 一项追溯性研究,涉及96名被诊断患有PP的女孩和96名健康对照.
- 进行了卵巢体积和骨年龄评估的盆腔超声波.
- 从2020年1月至2021年1月期间向儿科门诊报告的患者收集的数据.
主要成果:
- 卵巢体积>2.75预测了青春期早产的存在,敏感度为79.2%,特异性为90.6% (AUC:0.903).
- 在PP患者中,卵巢体积>3.25预测了2个或更多症状,敏感度为72.1%和特异性为98.1% (AUC:0.917).
- 在症状频率与卵巢体积增加和骨年龄之间发现了统计学上显著的相关性.
结论:
- 这项研究强调了早期青春期症状的数量与女孩的卵巢体积增加和骨年龄之间的显著相关性.
- 卵巢体积是早期青春期存在和严重性的有价值的预测指标.
- 这些发现强调了成像和骨年龄评估在早期青春期早期诊断中的重要性.
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