使用JOACMEQ评估的退行性宫肌病手术结果的临床指标:一个潜在的多中心研究
Narihito Nagoshi1,2, Junichi Yamane3,2, Toshiki Okubo1,2
1Department of Orthopaedic Surgery, Keio University School of Medicine, Tokyo, Japan.
Spine
|June 16, 2025
概括
手术改善了退行性宫骨髓病 (DCM) 患者的结果,但症状持续时间和残留疼痛等因素显著影响功能恢复和生活质量 (QOL).
科学领域:
- 神经外科 神经外科
- 整形外科 整形外科 整形外科
- 生活质量研究 研究 生命质量研究
背景情况:
- 退行性宫髓病 (DCM) 手术的目的是改善功能,但结果各不相同.
- 了解影响术后结果的因素对于患者管理至关重要.
研究的目的:
- 确定与DCM患者的术后功能和生活质量 (QOL) 结果相关的临床指标.
- 使用日本整形医学协会宫肌病评估问卷 (JOACMEQ) 进行全面的评估.
主要方法:
- 未来的多中心队列研究,包括日本852名DCM患者.
- 在2年后进行手术前后评估,使用JOA分数,VAS和JOACMEQ.
- 后勤回归分析以确定跨JOACMEQ领域有效结果的指标.
主要成果:
- 手术改善了JOA分数,并减少了疼痛.
- 根据JOACMEQ领域的有效率有所不同:宫功能 (49.6%),上肢 (48.5%),下肢 (35.1%),膀 (23.2%) 和QOL (23.8%).
- 较低的BMI,减少部疼痛,更短的症状持续时间,年轻的年龄和改善的四肢疼痛与更好的功能结果相关. 症状持续时间较长会对膀功能和QOL产生负面影响.
结论:
- 对DCM的手术干预通常会增强神经功能和缓解疼痛.
- 疾病持续时间,残留疼痛,年龄和BMI是术后身体功能和QOL的重要决定因素.
- 优化手术时间和知情同意对于改善DCM患者的治疗结果至关重要.
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