年龄,性别和区域/族裔差异的emmetropic轴增长率
Thomas Naduvilath1,2, Xiangui He3, Kathryn Saunders4
1Brien Holden Vision Institute (BHVI), Sydney, New South Wales, Australia.
概括
在6至16岁的年龄段,形轴向生长率是不均的,随着年龄的增长而下降,在男性中更高. 这些发现为近视治疗目标提供了洞察力.
科学领域:
- 眼科医生 眼科 眼科
- 人类成长和发展 人类成长和发展
- 人口健康 人口健康
背景情况:
- 轴长度延长是近视发展的一个关键因素.
- 对于预测折射误差进展而言,了解凝视性眼睛的特定年龄轴向生长模式至关重要.
- 基于人口的数据允许对性别和种族等增长决定因素进行可靠的分析.
研究的目的:
- 为了确定年龄特定的轴向生长率在眼 (正常视力) 的眼睛.
- 调查性别和地区/种族对轴向生长的影响.
- 为设定近视治疗目标提供数据.
主要方法:
- 对来自英国,瑞典和中国的6753名6至16.9岁参与者的16526个数据点进行了回顾性分析.
- 轴长用通用估计方程建模,考虑年龄,性别,种族,球体等价值 (SE) 和角膜半径.
- 特定于年龄的轴向增长率是通过保持恒定的SE和角膜曲率来得出的.
主要成果:
- 男性的轴长度比女性更长,东亚人的眼睛比欧洲人的眼睛长.
- 男性的轴增长率略高 (7%),但种族之间没有显著差异.
- 增长率非线性下降,从6岁时的0.17毫米/年 (男性) 和0.16毫米/年 (女性) 分别下降到16岁时的0.03毫米/年和0.02毫米/年.
结论:
- 恩米特罗普轴向增长率不均,在年幼的儿童和男性中更高.
- 估计的增长率与以前的研究相似或低于以前的研究.
- 这些精细的增长率估计可以为近视管理策略提供信息.
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