用植入的循环记录器评估心房动和疾病进展的循环模式
Daniel Camillo Spona1, Ketil Jørgen Haugan2, Claus Graff3
1Department of Cardiology, Copenhagen University Hospital-Rigshospitalet, Inge Lehmanns Vej 7, 2100 Copenhagen, Denmark.
European heart journal
|June 16, 2025
概括
心房动 (AF) 显示昼夜模式,通常在中午之前开始. 夜间AF发作更长,更慢,不同的患者群体表现出不同的AF负担和进展.
科学领域:
- 心脏病学 心脏病学
- 时间生物学 时间生物学
- 医疗器械技术 医疗器械技术
背景情况:
- 心房 (AF) 呈现出显著的异质性,需要改善患者的表型.
- 了解AF中的昼夜模式可以提供有关疾病特征和进展的见解.
研究的目的:
- 探索心房动 (AF) 发病和持续时间的昼夜模式.
- 调查AF时间对插曲特征和疾病进展的影响.
主要方法:
- 对LOOP研究的特例后分析,该研究涉及1410名具有AF风险因素的参与者.
- 从39个月的植入式循环记录器 (ILR) 数据中提取AF事件特征.
- K-意味着基于AF发病时间的不同患者组的分类.
主要成果:
- 分析了超过41,000个AF发作,最常见的发作发生在上午9点.
- 与白天发作相比,夜间AF发作 (晚上10点至早上7点) 较长,并与较慢的心室率相关.
- 两个患者群体出现了:午夜到早晨发病 (AF负担更高,进展更快) 和白天发病.
结论:
- 对于ILR检测到的AF,存在一个独特的昼夜模式,偏爱上午发作.
- AF表型各不相同,其特征是不同的发病时间和进展率.
- 研究结果建议探索基于AF模式的定时AF查和个性化治疗策略.
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