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Updated: Sep 19, 2025

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
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对GIP受体的治疗向 - - 重温争议

Jonathan E Campbell1, Daniel J Drucker2

  • 1Duke Molecular Physiology Institute, Durham, NC.

Diabetes
|June 16, 2025
PubMed
概括

针对体重管理的双受体向显示出有希望. 结合葡萄糖类1受体 (GLP-1R) 和依赖葡萄糖的胰岛素型多受体 (GIPR) 调制,无论是通过激动作用还是通过对抗作用,都会产生类似的减肥效果.

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