在基于模型的肺癌成本效益分析中,公布的证据是如何使用的?
Haijing Guan1,2, Chunping Wang3,4, Ruowei Xiao3,4
1Department of Pharmacy, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Health economics review
|June 16, 2025
概括
这项研究分析了肺癌成本效益分析 (CUA) 中的参数来源. 调查结果显示,数据引用和使用不一致的数据存在挑战,影响经济评估.
科学领域:
- 卫生经济学 卫生经济学
- 药物经济学 药物经济学
- 在瘤学瘤学.
背景情况:
- 基于模型的成本效益分析 (CUA) 对于评估肺癌治疗非常重要.
- 对肺癌中CUA的输入参数来源的证据有限.
- 本研究通过检查美国和中国的参数来源来解决这一差距.
研究的目的:
- 分析高级肺癌基于模型的CUA中临床疗效,安全性,成本和健康效用参数的来源.
- 为了比较美国和中国的参数来源和引用实践.
主要方法:
- 在美国和中国,对晚期肺癌治疗 (2018-2025) 的CUA进行系统审查.
- 参数来源的分类和对原始研究的引用路径的分析.
- 将参数数据与有关疾病和地区的原始研究进行比较.
主要成果:
- 分析了235项研究和10005个参数.
- 几乎一半的参数 (49.9%) 来自文献;17.7%来自无法识别的来源.
- 在美国和中国之间发现了疾病/地区 (30.8%) 和成本参数引用和实用数据使用的差异.
结论:
- 在参数引用和在肺癌CUAs中使用不一致的数据方面存在挑战.
- 提高透明度需要直接引用原始研究.
- 产生疾病和区域特定数据对于稳健的经济评估至关重要.
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