在健康的年轻人中,结构和功能连接的性别差异来自阿姆斯特丹公开MRI收藏
Xiaojian Kang1,2, Maheen M Adamson3,4, Byung C Yoon5
1WRIISC-Women, VA Palo Alto Health Care System, 3801 Miranda Avenue, Palo Alto, CA, USA. xkang@stanford.edu.
Brain structure & function
|June 16, 2025
概括
大脑结构和功能在两性之间存在差异,女性表现出较高的左半球结构和功能连接,特别是在语言和体运动网络中,为认知变异提供了洞察力.
科学领域:
- 神经科学是一个神经科学.
- 脑部成像 脑部成像
- 性别差异 性别差异
背景情况:
- 行为,认知和疾病的性别差异可能源于大脑变异.
- 了解这些差异对于个性化医学和神经科学研究至关重要.
研究的目的:
- 在健康的年轻成年人中调查结构连接 (SC) 和功能连接 (FC) 的性别差异.
- 探索这些差异如何与参与认知和行为的大脑网络有关.
主要方法:
- 在111名健康的右撇子年轻人中 (56名女性) 分析了SC和FC,使用基于集群和兴趣区域 (ROI) 的算法.
- 对大脑大小进行控制,以隔离性别特异性的影响.
主要成果:
- 在两性中观察到SC和FC之间的中等相关性,相关性强度没有显著差异.
- 与男性相比,女性在与语言网络相关的左半球区域表现出更高的SC.
- 雌性在体力运动和默认模式网络中显示出较高的左半球FC,以及半球之间较低的对称FC.
结论:
- 在年轻成年人的大脑结构和功能中存在显著的性别差异.
- 这些神经变异可能是语言处理,体运动知觉和其他认知功能中观察到的性别差异的基础.
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