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Updated: Sep 19, 2025

Investigation of the Transcriptional Role of a RUNX1 Intronic Silencer by CRISPR/Cas9 Ribonucleoprotein in Acute Myeloid Leukemia Cells
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分享的染色体重塑突变导致儿科患者同时患有拉布多米索瘤和白血病

Ji'ou Zhao1,2, Huimin Li1,2, Yongren Wang1,2

  • 1Department of Hematology, Children's Hospital of Nanjing Medical University, No. 72 Guangzhou Road, Nanjing, 210008, China.

Discover oncology
|June 16, 2025
PubMed
概括

研究了较为罕见的肌肉瘤 (RMS) 和B细胞急性淋巴细胞白血病 (B-ALL) 的同时发生情况. 确定了参与染色体重塑的五个关键驱动基因,这可能解释了这些罕见的儿科癌症中共享的分子机制.

关键词:
染色体重塑 染色体重塑 的方法在白血病中,白血病.拉布多米索尔科马 (Rhabdomyosarcoma) 是一种癌症.整个外基因组的测序.

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