强迫流离失所儿童群体的疫苗接种:系统性审查和元分析
Sargun Virk1,2, Andrew Milewski1,2, Nadia Khan3
1Human Rights Impact Lab, Weill Cornell Medical College, New York, New York.
JAMA network open
|June 16, 2025
概括
强迫流离失所儿童的疫苗接种率极低,为21%. 诸如监护人教育和住房稳定等因素增加了接种疫苗的几率,而流离失所本身减少了它们,突出了改善医疗保健策略的迫切需要.
科学领域:
- 全球健康 全球健康
- 儿童传染病 儿童传染病
- 强迫流离失所的人口
背景情况:
- 接种强迫流离失所的儿科人口进行疫苗接种存在重大挑战.
- 在这个脆弱群体中,确切的疫苗接种率在很大程度上是未知的,这阻碍了针对性的干预措施.
研究的目的:
- 估计强迫流离失所的儿科人口的疫苗接种覆盖率.
- 在这个人口群体中确定与疫苗接种状况相关的因素.
主要方法:
- 我们对六个数据库 (PubMed,EMBASE,MEDLINE,Scopus,Web of Science,Cochrane) 进行了系统审查和元分析.
- 包括的研究是关于流离失所儿童 (<19岁) 接种疫苗的原始研究文章.
- 用随机效应模型提取和合成数据,通过Downs和Black Checklist评估质量.
主要成果:
- 包括来自24个国家的39项研究,总体完整疫苗接种覆盖率为21% (95% CI,11%-36%).
- 与疫苗接种率增加相关的因素包括更大的家庭规模,更高的监护人教育,父亲的就业,更高的收入,住房稳定性和获得医疗保健.
- 相反,被迫流离失所与较低的疫苗接种率有关 (OR,0.70;aOR,0.73).
结论:
- 在被迫流离失所的儿科人口中,接种疫苗的覆盖率显著低.
- 这些发现强调了针对性医疗保健策略和政策的关键需求,以提高这一脆弱人群的免疫率.
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