公用水和出生结果在儿童健康结果上的环境影响 队列
Anne E Nigra1, Tessa R Bloomquist1, Tushara Rajeev1
1Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York.
JAMA network open
|June 16, 2025
概括
产前暴露于公共水中的,即使低于监管限制,也与低出生体重等不良出生结果有关. 减少饮用水中的含量可能会改善美国的婴儿健康.
科学领域:
- 环境健康 环境健康
- 生殖健康 生殖健康
- 毒理学 毒理学 毒理学
背景情况:
- 通过公共水道接触无机是一种公共卫生问题.
- 目前关于在低度下对出生结果的影响的证据有限.
- 饮用水中的联邦监管标准可能无法完全防止不良出生结果.
研究的目的:
- 调查美国环境保护局的最大污染物水平 (10微克/升) 以下公共水中的产前暴露与出生结果之间的关联.
- 为了评估早产,低出生体重和怀孕年龄小的风险.
主要方法:
- 来自环境影响儿童健康结果 (ECHO) 队列的数据分析,包括13,998名分娩父母-婴儿二合体.
- 使用住宅历史和邮政编码表格区域级数据估计个人,时间加权,产前公共水中暴露的平均值.
- 使用立方线模型对调整后的风险比率,出生体重的平均差异和妊娠年龄的统计评估.
主要成果:
- 产前公共水的暴露与低出生体重,低出生体重和较低的出生体重对妊娠年龄z-scores的风险增加有关,即使在10μg/L以下的水平.
- 在不同种族和民族群体中观察到相关性,在白色分娩父母中,对出生体重的影响更为明显.
- 没有发现种族和种族调解的证据.
结论:
- 公共水系统中的,度低于当前的联邦标准,与美国的不良出生结果有关.
- 研究结果表明,降低饮用水中的最大污染物水平可能会减少低出生体重婴儿的发生率.
- 进一步的研究和监管考虑是有必要的,以保护脆弱人群.
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