营养治疗是否会改变严重急性胰腺炎的病理生理学?
Lin Gao1,2, Yizhen Xu1, Lu Ke1,3,2
1Department of Critical Care Medicine, Jinling Hospital, Medical School of Nanjing University.
Current opinion in critical care
|June 16, 2025
概括
营养治疗可以影响严重急性胰腺炎 (SAP) 病理生理学和结果. 虽然早期肠道营养 (EN) 是有前途的,但需要更多高质量的证据来证实其益处.
科学领域:
- 临床营养学 临床营养学
- 胃肠病学 胃肠病学
- 关键护理医学 关键护理医学
背景情况:
- 严重的急性胰腺炎 (SAP) 涉及强烈的炎症和胃肠道功能障碍.
- 营养干预措施正在探索其改变SAP核心病理生理学的潜力.
研究的目的:
- 审查营养治疗在改变SAP病理生理学的作用.
- 评估营养治疗对SAP患者短期和长期临床结果的影响.
主要方法:
- 文献综述总结了SAP中营养治疗的当前证据.
- 对营养物质对炎症,肠道屏障功能和运动性的影响进行分析.
主要成果:
- 维生素C,D和omega-3脂肪酸等营养素可能会调节SAP中的炎症.
- 早期的肠道营养 (EN) 可以减少粘膜炎症并保护肠道屏障功能;谷氨酸可能提供额外的好处.
- 恩可以改善SAP中的运动性,但需要仔细监测缺血症;长期结果数据有限.
结论:
- 营养治疗具有干预SAP病理生理学和改善结果的潜力.
- 由于缺乏高质量的证据,需要进一步研究,特别是对长期影响.
相关概念视频
Acute Pancreatitis II: Clinical Manifestations and Management
186
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
186
Chronic Pancreatitis II: Collaborative Care
133
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Assessment:
133
Acute Pancreatitis I: Introduction
502
Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
502
Chronic Pancreatitis I: Introduction
173
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
173
Chronic Kidney Disease III: Interprofessional Care
87
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
87
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
309
Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
309


