肝移植患者的术后心血管评估和管理
Ali O Ibrahim1, Mohamed Salah Mohamed, Valentyna Ivanova
1Department of Cardiovascular Medicine, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA.
Current opinion in anaesthesiology
|June 16, 2025
概括
心血管疾病 (CVD) 对患有末期肝病 (ESLD) 的患者构成重大风险,特别是在肝移植 (LT) 期间. 标准化的心血管评估和管理对于改善患者的治疗结果和减少并发症至关重要.
科学领域:
- 心脏病学 心脏病学
- 肝病学 肝病学是一种肝病学.
- 移植医学 移植医学
背景情况:
- 心血管疾病 (CVD) 是最终阶段肝病 (ESLD) 患者的主要死亡原因,特别是在肝移植 (LT) 周围.
- 目前对ESLD患者的心血管风险评估和管理策略不一致.
- 本综述综合了ESLD患者经历LT的心血管问题的最新发现.
研究的目的:
- 审查最近在经过LT的ESLD患者心血管疾病的研究结果.
- 突出需要在这个人群中进行标准化的心血管评估和优化.
- 强调多学科方法对心血管管理的重要性.
主要方法:
- 关于ESLD患者心血管疾病最近发现的文献综述.
- 综合了关于肝硬化,门高血压和心血管功能障碍之间的相互作用的数据.
- 分析移植前查和风险分层方面的进展.
主要成果:
- 肝硬化有助于心血管功能障碍,包括肝硬化心肌病,冠状动脉疾病,心律失常和心力衰竭.
- 移植前查正在转向使用非侵入性成像和选择性冠状动脉血管学的风险分层方法.
- 心血管并发症在LT期间和之后很常见,免疫抑制可以增加长期心血管疾病风险.
结论:
- 跨学科的方法是管理心血管健康在ESLD患者经历LT. 管理必不可少的多学科方法.
- 标准化的手术前方案,精确的风险分层和基于证据的术后监测对于减少心血管疾病并发症至关重要.
- 未来的研究应该专注于优化干预措施,制定共识指导方针,并改善LT接受者的长期心血管护理.
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