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相关概念视频

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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Multimodal 3D Printing of Phantoms to Simulate Biological Tissue
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可3D打印的幻影用于定量动态增强对比度MRI.

M Sulaiman Sarwar1,2, Antoine Vallatos1,3, Cher Hon Lau4

  • 1Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.

Magnetic resonance in medicine
|June 16, 2025
PubMed
概括

新的3D打印幻影为验证定量动态增强对比度MRI (DCE-MRI) 测量提供了一种新方法. 这些幻影使得DCE-MRI数据的持续质量保证和多站点协调成为可能.

关键词:
通过3D打印打印3D打印.DCE DCE 是一个非常重要的组织.这就是为什么MRI是MRI.perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion 这种方法通常被认为是最常见的方法之一,它可以被认为是最常见的方法之一,它可以被认为是最常见的方法之一,因为它是最常见的方法之一.透性 透性的幽灵是什么意思 幽灵是什么意思

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科学领域:

  • 生物医学工程 生物医学工程
  • 医疗成像医学成像
  • 材料科学 材料科学 材料科学

背景情况:

  • 量化动态对比增强MRI (DCE-MRI) 需要强大的验证和标准化.
  • 目前的幻影可能无法完全复制与DCE-MRI分析相关的复杂生理参数.

研究的目的:

  • 引入一种新的3D打印幻影设计和技术验证,质量保证和定量DCE-MRI多站点协调的方法.
  • 评估3D打印参数与DCE-MRI模型输出之间的相关性.

主要方法:

  • 幻影是使用3D打印 (3DP) 的凝与集成的通道和毛孔模仿血管和细胞外空间制造的.
  • 一个流电路产生了临床相关的动脉输入功能.
  • 使用扩展的Tofts (ET) 模型分析了具有不同孔径和通道大小的9种凝,参数通过回归与物理性质相关.

主要成果:

  • 幻影产生了现实的动脉输入功能和类似组织的信号增强曲线,通过ET模型准确地建模.
  • 血体积分数 (vp) 与通道体积分数 (vchan) 有正相关,与凝多孔性 (vpore) 有负相关.
  • 血管透率-表面积产物 (PS) 与vchan和vpore都有正相关. 外血管细胞外空间 (EES) 体积分数 (ve) 与v孔正相关.
  • 装配的DCE-MRI参数显示出高可重现性 (2.1%-3.2%的变化系数).

结论:

  • 可形3D打印的多孔凝幽灵有效地模仿DCE-MRI的组织特征.
  • 这些幻影显示出支持定量DCE-MRI测量的验证,质量保证和多站点协调的巨大潜力.