摄入单个水解原蛋白球体与自由氨基酸对肌肉连接蛋白质合成率的影响
Thorben Aussieker1, Jeremias Kaiser1, Floris K Hendriks1
1Department of Human Biology, Institute of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University Medical Centre, Maastricht, THE NETHERLANDS.
Medicine and science in sports and exercise
|June 16, 2025
概括
在健康的成年人中,摄入水解原蛋白或自由氨基酸会增加氨基酸水平,但不会提高休息或运动后的肌肉蛋白质合成率.
科学领域:
- 运动生理学 运动生理学
- 营养生物化学 营养生物化学
- 肌肉的新陈代谢
背景情况:
- 饮食中的蛋白质摄入对于肌肉的修复和生长至关重要.
- 水解原蛋白和自由氨基酸是运动员的热门补充剂.
- 了解它们对肌肉蛋白质合成的影响对于优化训练和恢复至关重要.
研究的目的:
- 为了评估单剂量水解原体或自由氨基酸对肌肉蛋白质合成的影响.
- 在年轻,健康的成年人中,将这些效应与安慰剂进行比较.
主要方法:
- 一项随机,双盲,并行研究,涉及45名参与者.
- 参与者接受了L-[环-13C6]-氨输注.
- 在单方面抵抗运动后摄入水解原蛋白,自由氨基酸或安慰剂.
主要成果:
- 原蛋白和氨基酸补充剂都显著增加了循环氨基酸度.
- 两者都不补充显著增加的肌纤维细胞蛋白质合成率.
- 肌肉连接蛋白质合成率也在摄入后保持不变.
结论:
- 一个单一的原解液或自由氨基酸可增加循环氨基酸,但不能增强肌肉蛋白质合成.
- 这些发现表明,单独的原蛋白或自由氨基酸可能不足以刺激肌肉蛋白质合成,超过健康年轻人基础水平.
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