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Updated: Sep 19, 2025

Molecular Modulation by Lentivirus-Delivered Specific shRNAs in Endoplasmic Reticulum Stressed Neurons
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Published on: April 24, 2021

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复星衍生物SH-707通过一种依赖于1素的通路抑制NLRP3炎症酶激活

Kyung Tae Kim1, Jong Beom Heo2, Taylor Roh3

  • 1Department of Microbiology, Chungnam National University College of Medicine, Daejeon 35015, Republic of Korea; Department of Medical Science, Chungnam National University College of Medicine, Daejeon 35015, Republic of Korea; System Network Inflammation Control Research Center, Chungnam National University College of Medicine, Daejeon 35015, Republic of Korea.

International immunopharmacology
|June 16, 2025
PubMed
概括

瑞斯韦拉衍生物SH-707通过抑制NLRP3炎症酶和减少IL-1β.有效治疗败血症. 这种新型化合物显示出对炎症性疾病的治疗潜力.

关键词:
一个IL-1ββ.在NLRP3炎症酶体中,NLRP3炎症热性灭症 (Pyroptosis) 是一种复星醇是一种复星.一个SIRT1系统.

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