腺瘤检测率与流行结肠直肠癌检测率在国家结肠镜注册表中的关联
Jason A Dominitz1, Uri Ladabaum2, Jennifer L Holub3
1National Gastroenterology and Hepatology Program, Veterans Health Administration, Washington, District of Columbia; National Colorectal Cancer Screening Program, Veterans Health Administration, Washington, District of Columbia; Division of Gastroenterology, Department of Medicine, University of Washington School of Medicine, Seattle, Washington.
Gastroenterology
|June 16, 2025
概括
在结肠镜检查中,较高的腺瘤检测率 (ADR) 与结肠直肠癌 (CRC) 的检测率增加相关. 这表明ADR反映了错过的CRC和癌前病变,强调了医生ADR对CRC预防的重要性.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 腺瘤检测率 (ADR) 与结肠镜后结肠直肠癌 (CRC) 风险有关.
- 对ADR反映错过的CRC与癌前病变的程度尚不清楚.
研究的目的:
- 评估医生ADR与在结肠镜检查期间发现流行CRC之间的关联.
主要方法:
- 由3567名内镜医生对超过173万次结肠镜 (2019-2022) 的截面数据进行分析.
- 根据查检查,确定内镜的ADR和形形病变检测率 (SSLDR).
主要成果:
- 在查和后续结肠镜检查中,CRC检测增加了更高的内镜ADR五分之一.
- 较高的ADR五分位数与CRC检测的几率增加有关 (OR 1.27-1.50).
- 低ADR的内镜显示较低的CRC检测率,无论SSLDR.
结论:
- 医生ADR反映了CRC检测和CRC前体的识别/去除.
- 结肠镜后CRC可能经常是错过CRC的结果,特别是在具有低ADR的内镜师身上.
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