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多个活跃基因组修饰的协调作用塑造了teleost胚胎中囊胚基因组的激活

Hiroto S Fukushima1,2, Hiroyuki Takeda3,4

  • 1Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan. hiroto.fukushima@riken.jp.

Nature communications
|June 16, 2025
PubMed
概括

紫毒基因组激活 (ZGA) 涉及对发育和家政基因的明显的组素修饰. CBP/P300活动对发育基因至关重要,而其他基因则在脊椎动物早期发育过程中调节家政基因.

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