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Updated: Sep 19, 2025

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
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质子抑制剂增加C. 通过改变pH值而不是通过影响基于生物反应器模型的肠道微生物群来增加困难感染风险

Julia Schumacher1,2, Patrick Müller1,3,4, Johannes Sulzer5,6

  • 1Cluster of Excellence EXC 2124 Controlling Microbes to Fight Infections, University of Tübingen, Tübingen, Germany.

Gut microbes
|June 17, 2025
PubMed
概括

质子抑制剂 (PPI) 治疗增加了Clostridioides difficile感染的风险,主要是由于胃肠道pH值的变化,而不是药物对肠道微生物群的直接影响. 这一发现影响了理解与PPI使用相关的感染风险.

关键词:
质子抑制剂 质子抑制剂生物反应器是一个生物反应器.克洛斯特里迪奥伊德困难感染.殖民化 抵抗 抵制我们的肠道微生物群.

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