空气污染和喘和非喘儿童的肺功能:一个横截面研究,在胡志明市进行了嵌套病例对照分析
Quynh Nhat Nguyen1, Thao Phuong Mai1, An Le Pham1
1Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Tropical medicine & international health : TM & IH
|June 17, 2025
概括
空气污染对儿童的呼吸健康产生负面影响,导致肺功能下降和呼吸道炎症增加,特别是在患有喘的人群中. 减少室内和室外空气污染对于保护儿童的肺部健康至关重要.
科学领域:
- 环境健康 环境健康
- 儿科肺病学 儿科肺病学
- 流行病学 流行病学
背景情况:
- 在全球范围内,儿童喘患病率正在上升.
- 空气污染是已知的呼吸道疾病的风险因素.
- 了解特定污染物对儿科呼吸系统健康的影响至关重要.
研究的目的:
- 调查空气污染暴露与儿童呼吸道健康指标之间的关联.
- 为了比较这些协会在稳定的喘与非喘儿童.
- 识别特定的室内和室外空气污染物,影响儿科肺功能和炎症.
主要方法:
- 一项横截面研究,在胡志明市进行了嵌套病例控制分析.
- 参与的36名喘和81名非喘儿童 (年龄12-14岁) 在倾向性得分匹配后.
- 收集了关于螺旋计,部分呼出的氧化 (FeNO) 和空气污染 (PM2.5,蚊子线圈使用,窗户打开) 的数据.
主要成果:
- 对空气污染的暴露与儿童的肺功能减弱和FeNO增加有关.
- 在喘患者中,蚊子卷使用与FEV1/FVC显著下降,FEF25-75下降和FeNO增加相关.
- 在非喘患者中,PM2.5的增加和窗口的打开与FEV1/FVC和FEF25-75的下降有关.
结论:
- 空气污染显著影响儿科呼吸系统健康,对喘儿童有明显的影响.
- 特定的室内 (蚊子卷) 和室外 (PM2.5) 污染物加剧肺功能下降和炎症.
- 紧急干预以减少空气污染是必要的,以保护儿童的呼吸健康.
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