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与百日咳相关的超白细胞症:两个病例报告.
Hong-Wu Han1, Xi-Xia Wang1, Ying Wang2
1Department of Pediatric, Shaanxi University of Chinese Medicine, Xianyang 712046, Shaanxi Province, China.
World journal of clinical cases
|June 17, 2025
概括
在儿童中,严重的百日咳可能导致死亡,特别是在超白细胞症中. 早期识别和血交换治疗可以改善这些关键病例的结果并降低死亡率.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 血液学 血液学 血液学
背景情况:
- 由于*Bordetella pertussis*引起的百日咳仍然是婴儿和儿童严重呼吸系统疾病和死亡的重要原因,尽管疫苗接种广泛.
- 超白细胞症,以极高的白细胞计数为特征,是与严重咳和死亡风险增加相关的关键因素.
- 血交换是一种成熟的临床方法,用于在严重条件下降低白细胞计数.
研究的目的:
- 突出高白细胞症在严重儿科 pertussis 中的关键作用.
- 介绍一系列案例,证明血交换在治疗因高白细胞症复杂的严重百日咳的疗效.
- 强调早期干预对改善患者结果的重要性.
主要方法:
- 两名患有 pertussis 的儿科患者的病例报告,出现咳和随后的肺炎.
- 监测显著增加的白细胞计数,达到87.34×10^9/L和55.46×10^9/L.
- 治疗包括抗感染疗法,血交换和呼吸系统支持.
主要成果:
- 这两名儿科患者都经历了严重的百日咳,最初出现了咳症状和肺炎的发展.
- 在这两种病例中都观察到极端白细胞症,表明严重的疾病状态.
- 经过包括血交换在内的综合治疗,两个孩子都完全康复了.
结论:
- 在儿童中,因高白血细胞症而复杂的百日咳的早期诊断对于及时干预至关重要.
- 及时服用血交换疗法可以显著改善预后,并降低严重儿科百日咳病例的死亡率.
- 积极的管理策略,包括血交换,对于管理咳中危及生命的超白细胞瘤至关重要.
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