巴西社区老年人处方模式和药物治疗风险:一项跨部门研究
Isadora F Odebrecht1, Ana Beatriz F Nascimento1, Diogo N Silveira1
1School of Medicine, Pontifical Catholic University of Parana (PUCPR), Londrina, BRA.
多药性药物显著增加了老年人的药物治疗风险,强调了需要更好的药物管理和减少处方教育的需要. 这项研究在巴西老年人中发现了潜在不合适药物和非处方药的使用率很高.
科学领域:
- 老年人药理学 老年人药理学
- 公共卫生 公共卫生
- 药物安全 药物安全
背景情况:
- 多药和接触潜在不合适药物 (PIMs) 是老年护理中的重大挑战.
- 老年人复杂的治疗方案会增加药物治疗风险.
- 这项研究探讨了巴西社区老年人的处方模式和风险.
研究的目的:
- 为了确定在巴西社区居住的老年人处方模式.
- 评估与这种人群中药物使用相关的药物治疗风险.
- 调查多药学和药物治疗风险之间的关系.
主要方法:
- 对504名身体独立的老年人进行横截面研究.
- 数据收集包括社会人口统计,并发症和所有当前药物 (处方药,替代药,OTC).
- 使用Beers 2023标准识别的潜在不合适药物 (PIMs);通过PIM或OTC使用分层的药物治疗风险.
主要成果:
- 多药性影响了26.98%的参与者,36.0%使用PIM,而19.2%使用OTC药物.
- 大约40.7%的老年人被归类为药物治疗风险.
- 多药与药物治疗风险的增加密切相关 (OR = 4.9,p = 0.001).
结论:
- 居住在社区的老年人表现出显著的药物治疗风险,主要是由多药制造成的.
- 加强医疗教育合理使用药物和减缓处方对于减轻不良后果至关重要.
- 未来的研究应该探索技术解决方案,以支持老年人安全的药物管理和停药.
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