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Updated: Sep 19, 2025

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
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在chr11p11.2处的非编码调节变异rs2863002通过影响HSD17B12表达和脂质代谢增加神经母细胞瘤风险

Teresa Maiorino1,2, Marianna Avitabile1, Vincenzo Aievola1,2

  • 1Department of Molecular Medicine and Medical Biotechnology at University of Naples "Federico II", Naples, 80131, Italy.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|June 17, 2025
PubMed
概括

一项全基因组关联研究发现了神经母细胞瘤风险基因在chr11p11.2.2. rs2863002变种调节HSD17B12,影响脂质代谢和神经母细胞瘤的发展.

关键词:
在HSD17B12中使用.在GWAS中,GWAS就是GWAS.在SNP中,SNP是SNP.功能性基因组学 功能性基因组学遗传倾向 遗传倾向 遗传倾向脂质新陈代谢 脂质新陈代谢神经母细胞瘤的神经母细胞瘤

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