与疾病相关的嗅觉障碍中的与年龄相关的恶化
H Shimmura1, E Mori1, R Sekine2
1Department of Otorhinolaryngology, The Jikei University School of Medicine Hospital, Tokyo, Japan.
Rhinology
|June 17, 2025
概括
衰老在某些嗅觉障碍 (OD) 中显著影响嗅觉功能,包括非eosinophilic慢性鼻炎,后感染性OD和异常性OD. 然而,年龄并没有显著影响eosinophilic慢性鼻炎或创伤后OD的嗅觉功能.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 老年学是指老年学的学科.
- 神经科学是一个神经科学.
背景情况:
- 嗅觉功能障碍 (OD) 受衰老和疾病的影响.
- 有限的流行病学数据存在于OD原因中衰老的作用.
- 这项研究调查了年龄对主要OD病因学的影响.
研究的目的:
- 确定老化如何影响OD主要原因的患者的嗅觉功能.
- 分析各种OD类型的嗅觉感官测试结果的年龄相关差异.
- 根据年龄和性别来评估重度OD的几率.
主要方法:
- 1986年从一个气味诊所的患者的回顾性分析.
- 使用T&T嗅计值评估的定量嗅觉功能.
- 根据年龄 (20至80岁) 划分患者;分析年龄组和疾病差异;根据年龄 (<60至≥60) 和性别划分重度OD的几率比率.
主要成果:
- 与年龄相关的嗅觉值 (检测和识别) 显著下降,观察到非埃索诺菲尔性慢性鼻炎,后感染性OD和异常性OD.
- 在异性慢性鼻炎或创伤后的OD中没有发现对嗅觉值的显著年龄影响.
- 几率比率分析表明,在特定条件下,年龄是严重的OD的重要因素.
结论:
- 与年龄相关的嗅觉变化在不同的OD条件中存在显著差异.
- 临床医生必须考虑年龄和特定疾病病理学来准确诊断和管理OD,特别是在老年人中.
- 研究结果强调了老化对嗅觉功能的不同影响,这取决于OD的根本原因.
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