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在急性医院环境中,与酒精有关的认知障碍的死亡结果

Helen White^1,2, Lynn Owens^1,2, Edward Britton¹

¹Hepatology Department, Royal Liverpool University Hospital, Mount Vernon Street, Liverpool, L7 8YE, United Kingdom.

Alcohol and alcoholism (Oxford, Oxfordshire)

|June 17, 2025

概括

与酒精有关的认知障碍 (ARCI) 与早期死亡率有关,特别是肝脏疾病. 早期干预可以改善ARCI患者的治疗结果.

科学领域:

神经学神经学
肝病学肝病学是一种肝病学.
公共卫生公共卫生

背景情况:

与酒精有关的认知障碍 (ARCI) 对治疗参与和患者的结果产生负面影响.
在急性医院环境中识别ARCI对于了解长期健康后果至关重要.

研究的目的:

描述在急性医院环境中被诊断患有ARCI的患者的遗留队列中的结果.
调查ARCI,慢性肝病 (CLD) 和死亡率之间的关联.
评估参与ARCI护理途径对患者结果的影响.

主要方法:

在2017年4月至2018年3月期间对ARCI进行查的210名患者的回顾性审查.
排除具有其他认知障碍原因的患者.
利用蒙特利尔认知评估 (MoCA) 进行诊断和严重程度评估,随后通过多学科团队 (MDT) 转诊.
记录了使用考克斯回归分析和卡普兰-梅尔图表的3年死亡率.

主要成果:

ARCI与3年死亡率有显著的相关性 (HR1.732,p=0.019).
同时存在的慢性肝病 (CLD) 放大了这种关联 (HR 1.722, p=0.020),尽管单独的CLD并没有增加死亡风险 (HR 1.223, p=0.401).
严重的ARCI显示出与死亡率的最强相关性 (p<0.001),而参与ARCI护理途径改善了结果 (HR 0.324,p=0.008).

结论:

通过简单的床边测试确定的ARCI与早逝率有显著的联系.
这种关联在患有同时存在的肝病和ARCI严重程度增加的患者中更为明显.
早期参与专门的ARCI护理途径证明了对患者结果的积极影响.

关键词:

这就是ARBI ARBI.在 ARCI 里面,你会看到 ARCI.这就是MoCA MoCA.与酒精有关的认知障碍死亡率死亡率结果就是结果.

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