点对点:级联报告 - - 支持抗菌药物管理的有用工具,或危险地误导
Joseph L Kuti1, Joseph D Lutgring2, Patricia J Simner3,4
1Center for Anti-Infective Research and Development, Hartford Hospital, Hartford, Connecticut, USA.
对抗微生物敏感性测试 (AST) 的级联报告可以减少广泛的抗微生物使用和抗药性. 仔细实施是最大限度地提高效益的关键,同时最大限度地降低患者护理和公共卫生监测的风险.
科学领域:
- 临床微生物学 临床微生物学
- 传染性疾病 传染性疾病
- 抗微生物药物管理委员会
背景情况:
- 抗菌素耐药性 (AMR) 需要多学科策略,包括临床实验室的参与.
- 对抗微生物敏感性测试 (AST) 的级联报告旨在促进窄谱抗微生物药物的使用.
- 有关实施复杂性,长期处方影响,合规性和公共卫生监测存在担忧.
研究的目的:
- 评估实施AST级联报告的好处和风险.
- 探讨专家对级报告的有效性和挑战的意见.
主要方法:
- 对AST级联报告现有文献和专家共识的审查.
- 对抗微生物药物处方和耐药性模式的潜在影响的分析.
主要成果:
- 级联报告可以减少广泛的抗微生物药物的使用和降低耐药率.
- 实施挑战包括复杂性,对处方行为的潜在影响和监控问题.
- 专家的共识支持级联报告作为抗菌药物管理的工具.
结论:
- AST级联报告为抗微生物药物管理提供了好处.
- 谨慎的协议设计和实施对于减轻患者和公共卫生监测风险至关重要.
- 优化级联报告需要平衡抗菌药物管理目标与潜在的实施障碍.
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