核心时钟基因的功能障碍调节了胆管癌细胞的恶性表型和gemcitabine敏感性

Yin Li1, Aimin Zheng1, Yangang Cui1

  • 1Department of Oncology.

Anti-cancer drugs
|June 17, 2025
PubMed
概括

循环时钟基因影响胆管癌 (CCA) 恶性. BMAL1和NR1D1的丧失促进了入侵和耐吉他的抵抗,而PER2抑制提高了化学敏感性,并减少了CCA中的转移.

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