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实现基于计算的独立剂量验证在质子疗法中的实施

Nichakan Chatchumnan¹, Mananchaya Vimolnoch¹, Sakda Kingkaew¹

¹Division of Radiation Oncology, Department of Radiology, King Chulalongkorn Memorial Hospital, The Thai Red Cross Society, Bangkok, Thailand.

|June 17, 2025

概括

使用蒙特卡洛模拟的独立剂量计算可用于质子疗法质量保证. 该方法为临床环境提供可靠的二次剂量验证,确保治疗的准确性.

科学领域:

医学物理医学物理
辐射瘤学辐射瘤学
计算剂量计计算剂量计.

背景情况:

质子疗法提供精确的瘤向与最小的健康组织损伤.
使用蒙特卡洛模拟的独立剂量计算是患者特异性质量保证 (PSQA) 的关键二次验证工具.

研究的目的:

在质子疗法中实施PSQA的独立剂量计算.
为了建立这个验证方法的信任度,容忍度和行动极限.

主要方法:

使用电离室进行点剂量验证.
对单个和多个能量计划的独立和治疗规划计算之间的剂量分布进行了比较.
马分析 (3%/3mm和5%/3mm) 应用于五个解剖区域的50个临床计划.

主要成果:

测量和独立计算之间的剂量差异在1.0%以内.
在多个能源计划中,Gamma通过率超过98.0%,在所有地点均为95.9% (3%/3mm) 和97.9% (5%/3mm).
确定的信心,耐受性和作用极限在85.4%至94.3%之间,取决于玛标准.

结论:

独立剂量计算是质子治疗中PSQA可行的二次剂量验证方法.
这种方法可以提高繁忙的诊所的效率.
仔细考虑信心,耐受性和作用极限对于可靠的质子疗法治疗是必不可少的.

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