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具有细胞活动的KMT9抑制剂原药的结构导向设计

Sheng Wang1, Nicolas P F Barthes2, Sylvia Urban1

  • 1Klinik für Urologie und Zentrale Klinische Forschung, Klinikum der Albert-Ludwigs-Universität Freiburg, Freiburg 79106, Germany.

Journal of medicinal chemistry
|June 17, 2025
PubMed
概括

研究人员开发了强大的KMT9抑制剂用于癌症治疗. 一种前药物形式有效地抑制了结肠癌细胞的增殖,验证了KMT9作为治疗点.

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