穿皮声类固醇注射:目前对指示和技术的重新评估
Leonardo Franz1, Giovanna Baracca1, Alessandro Matarazzo1
1Phoniatrics and Audiology Unit, Department of Neuroscience DNS, University of Padova, Treviso, Italy.
American journal of otolaryngology
|June 17, 2025
概括
通过皮肤注射声类固醇注射对良性喉病变,如结节和息肉,显示出有前途. 需要进一步的多中心研究来确认有效性和通用性.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 喉腔病理学 喉腔病理学
- 干预性肺病学 干预性肺病学
背景情况:
- 类固醇注射被探索为良性声病变,因为他们的炎症性质.
- 虽然通过鼻子进行的方法已经有证据,但通过宫穿透皮肤方法的证据是有限的.
研究的目的:
- 批判性地审查针对良性喉病变的皮肤注射类固醇的证据.
- 要总结这种治疗方式的指示,技术和结果.
主要方法:
- 在PubMed和Scopus数据库中的系统文献搜索.
- 使用PRISMA指南的文章选,包括关于皮肤声类固醇注射的原始报告.
- 排除数据不足的研究,单一病例或非原始研究.
主要成果:
- 从603篇获取的论文中包含了16篇文章.
- 治疗的病变包括结节,多,颗粒瘤,纤维化,狭窄和雷恩克.
- 使用的穿皮途径是跨甲状腺,跨胆固醇和跨甲状腺软骨.
结论:
- 通过皮肤注射声类固醇注射对于良性喉病变似乎是可行的和有效的.
- 结节和息肉可能比其他类型的病变更好地反应.
- 异质性需要进一步的前性,多中心研究,以获得确的数据.
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