在椎脊髓损伤患者中Ipsilateral皮质运动通路的特征 脊髓损伤
Jia Liu1, Madeline Cantu2, Kyle O'Laughlin1
1Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.
概括
四肢的ipsilateral运动路径与手臂功能有关,即使在唤起的潜力中没有直接差异. 这表明这些途径在脊髓损伤 (SCI) 的康复策略中可能发挥作用.
科学领域:
- 神经科学是一个神经科学.
- 运动生理学 运动生理学
- 脊髓损伤研究 脊髓损伤研究
背景情况:
- 对四肢的有效上肢治疗需要了解运动神经生理学.
- 在椎脊髓损伤 (SCI) 中,研究在很大程度上忽视了ipsilateral运动通路.
研究的目的:
- 为了研究四肢患者的ipsilateral运动通路的神经生理学.
- 探索四肢的双侧生理和上肢功能之间的关系.
主要方法:
- 经磁刺激 (TMS) 用于评估双肩肌肉中的两侧和两侧运动唤起潜力 (MEP).
- 23名四肢患者和24名对照参与了这项研究.
- 在四肢症组中评估了上肢功能和性.
主要成果:
- 在四肢和对照组之间,在ipsilateral motor evoked potential (iMEP) 特征中没有发现显著差异.
- 在四肢患者中,较大的iMEP振幅与较大的对侧MEP振幅相关.
- 在四肢症组中,更大的iMEP振幅也与更好的近端手臂运动功能有关.
结论:
- 在四肢的个体中,ipsilateral运动生理与 contralateral生理和近端手臂功能相互关联.
- 侧路径可能有助于SCI后近端手臂功能.
- 未来的研究应该检查未保存的肌肉中的iMEP,以了解受伤特异性适应用于康复.
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