在产科患者中查青素过敏,以优化指导方针导向治疗
Kayla Godfrey1, Deanna McDanel1,2, Kelly Percival1
1University of Iowa Health Care, Iowa City, IA, USA.
概括
在孕妇中对青素过敏的测试是安全有效的. 删除过敏标签增加了在分娩期间推使用的抗生素B组链球菌 (GBS) 预防.
科学领域:
- 产科和妇科 产科和妇科
- 过敏和免疫学 过敏和免疫学
- 传染性疾病 传染性疾病
背景情况:
- 青素过敏标签在产科患者中很常见.
- 准确的青素过敏评估对于适当的产后抗生素预防至关重要.
研究的目的:
- 为了评估青素过敏测试在产科患者的安全性.
- 为了确定是否取消标签的青素过敏增加了指导方针推的抗生素使用B组链球菌 (GBS) 预防.
主要方法:
- 对带有青素过敏标签的产科患者进行了回顾性队列研究.
- 评估包括有或没有青素皮肤测试 (PST) 的口服药物挑战.
主要成果:
- 评估的90.3%的患者的青素过敏被取消了标签.
- 在口服药物挑战期间没有发生过敏反应.
- 被取消标签的患者更有可能接受青素G用于GBS预防 (87.5%vs24.5%).
结论:
- 药物过敏测试在产科患者中是安全的.
- 大多数患者可以接受直接口服挑战或PST,然后再进行挑战.
- 在分娩前对青素过敏的评估增加了适当的GBS预防.
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