动脉瘤血液动力学分析的综合多学科方法:数值模拟,体外实验和深度学习
Tingting Fan1, Jinhang Wang1, Xu Wang2,3
1School of Biomedical Engineering, Capital Medical University, Beijing, China.
Frontiers in bioengineering and biotechnology
|June 18, 2025
概括
本综述探讨了血流动力学 (血液动力学) 如何影响动脉瘤的发展和进展. 它强调了先进的分析方法,旨在改善患者特异性风险评估,以便更好地进行临床干预.
科学领域:
- 心血管科学 心血管科学
- 生物医学工程 生物医学工程
- 计算流体动力学的流体动力学.
背景情况:
- 动脉瘤是一种危及生命的血管疾病,受到血液动力学显著影响.
- 数字模拟和体外实验使得高精度的血液动力学分析成为可能.
- 深度学习提高了计算效率,但在仿生材料和机械生物合方面仍然存在挑战.
研究的目的:
- 审查用于表征动脉瘤进展中的血液动力学扰乱的方法.
- 阐明动脉瘤破坏稳定的机制基础.
- 激发标准化血液动力学分析协议和患者特异性风险分层.
主要方法:
- 传统和新兴的血液动力学分析方法的系统化.
- 数字模拟,体外实验和深度学习的整合.
- 通过病理生理连续的分析:扩张,破裂和血栓形成.
主要成果:
- 血液动力学因素对动脉瘤的发展和进展至关重要.
- 先进的计算和实验技术正在改善分析.
- 在仿生材料和理解机械生物合方面存在差距.
结论:
- 了解血液动力学干扰是阐明动脉瘤不稳定性的关键.
- 为了准确的血液动力学分析,需要标准化的协议.
- 数据驱动的临床干预和患者特异性风险分层是未来.
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