研究重点和肠道微生物群与神经炎症之间的关联趋势
Shan Wu1,2, Nanjie Chen3, Chuanchi Wang2,4
1Guangdong-Hong Kong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou, China.
Frontiers in microbiology
|June 18, 2025
概括
对肠道微生物群和神经炎症的研究正在迅速增长,突出显示微生物群-肠道-大脑轴. 这项研究分析了1,404篇论文,绘制了这一关键领域的研究趋势和未来方向.
科学领域:
- 神经科学是一个神经科学.
- 微生物学 微生物学
- 免疫学 免疫学 免疫学
背景情况:
- 肠道微生物群与宿主之间的相互作用显著影响神经炎症,这是神经退行性疾病的关键因素.
- 尽管越来越多的研究,但缺乏对肠道微生物群和神经炎症数据的全面分析.
- 了解这些机制对于开发新的治疗策略至关重要.
研究的目的:
- 系统地分析有关肠道微生物群和神经炎症机制的临床实践和研究热点.
- 提供对该领域的图书统计和基于可视化的概述.
- 确定未来的研究途径和发展机会.
主要方法:
- 从Web of Science核心集合 (2000-2024) 中对1,404项研究进行了图书统计分析.
- 使用软件,包括CiteSpace和VOSviewer用于可视化.
- 检查了文献合作,作者/国家结构,关键字的共同出现和新出现的参考.
主要成果:
- 从2000年到2024年,关于肠道微生物群和神经炎症的出版物出现了显著的上升趋势,在2020年达到引用峰值.
- 中国和美国是主要的贡献者.
- 研究强调微生物群-肠-大脑轴机制,治疗方法包括益生菌,便微生物群移植和传统中医药.
结论:
- 这项研究提供了关于肠道微生物群与神经炎症相关的研究进展的全面审查.
- 它确定了当前的研究重点和前沿方向.
- 为这个跨学科领域的未来发展提供了宝贵的参考.
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