通过心脏磁共振特征追踪评估的甲状腺功能过高患者的早期心脏参与
Yi Zhang1, Yiming Jia2, Renbin Ge1
1Department of Radiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Frontiers in endocrinology
|June 18, 2025
概括
左心房应变有效地检测高甲状腺症患者的早期心脏问题. 这种方法优于体积参数和心室应变来诊断心肌损伤.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 内分泌学 在内分泌学.
背景情况:
- 甲状腺功能障碍会导致心肌损伤的早期阶段.
- 评估甲状腺功能障碍的心脏参与对于及时干预至关重要.
研究的目的:
- 评估使用心肌菌株用于定量评估高甲状腺症早期心肌损伤的可行性.
- 为了比较左心房 (LA) 应变和左心室 (LV) 参数在检测心脏参与方面的诊断值.
主要方法:
- 心血管磁共振 (CMR) 用于评估45名甲状腺功能障碍患者和26名对照者的心脏功能.
- 测量包括LV体积,LV质量指数 (LVMi),LV喷射率 (LVEF),心肌应变和LA排空率 (TEF,PEF,AEF).
- 根据心房动 (AF) 的存在或不存在来对患者进行分类.
主要成果:
- 在所有甲状腺功能增高患者中,左心房 (LA) 储,导管和助推菌株显著受损 (p < 0.01).
- 左心室 (LV) 参数和心肌张力在没有AF的甲状腺功能增高患者和对照人群之间没有显著差异 (p > 0.05).
- 与没有AF的患者相比,甲状腺功能障碍的甲状腺功能障碍患者的LA活性空化分数 (AEF) 和LVEF降低了.
结论:
- 左心房 (LA) 应变是甲状腺功能增强症早期心脏参与的可靠指标.
- 卷度参数和心室肌肉应变在检测这群人早期心脏变化方面效率较低.
- 在区分甲状腺功能障碍患者和对照者方面,LA储菌株表现出高的诊断准确性 (80.8%的灵敏度,80%的特异性).
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