功能性心声学确定了早期心室功能障碍与儿科败血症的结果之间的关联
Sonia Reveco1,2, Stella Barbagelata1,3, Pablo Cruces1,4
1Pediatric Intensive Care Unit, Hospital El Carmen Dr Luis Valentin Ferrada, Santiago, Chile.
Frontiers in pediatrics
|June 18, 2025
概括
患有心室功能障碍的儿科败血症患者经历了更严重的疾病和更少的非重症监护病房日. 心声扫描显示这些儿童的异常组织多普勒测量结果.
科学领域:
- 儿科重症监护医药 儿科重症监护医药
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
背景情况:
- 儿科败血症是一种危及生命的疾病.
- 心室功能障碍是败血症的一个潜在并发症.
- 早期识别心室功能障碍可能会改善结果.
研究的目的:
- 调查心室功能障碍与儿科败血症临床结果之间的关联.
- 描述在患有败血症的重症儿童中评估腹腔功能的可行性.
主要方法:
- 在两个儿科重症监护病房 (PICU) 进行前性观察研究.
- 纳入51名患有败血症或败血性休克的儿科患者 (15岁以下).
- 在入院后24小时内进行功能性心声扫描;腹腔功能障碍以静脉/腹腔异常来定义.
主要成果:
- 四分之一的患者患有心室功能障碍.
- 心室功能障碍与较高的败血症休克率 (69.2%对34.2%),较高的pSOFA得分 (92%对64%) 和较少的无PICU日 (18对23) 有关.
- 异常组织多普勒测量,包括较低的S波和E波Z分数,在心室功能障碍患者中更频繁.
结论:
- 儿科败血症中心室功能障碍与疾病严重程度的增加和较差的结果有关,包括更少的无重症监护病房日.
- 组织多普勒参数与该人群中心室功能障碍的存在相关.
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