探索以性别为主题的素酸二甲基胺体验:一个子reddit分析
Rahul Katkar1, Ashley M Perez1, Murat Altinay2
1Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Psychedelic medicine (New Rochelle, N.Y.)
|June 18, 2025
概括
Lysergic acid diethylamide (LSD) 的体验可能有助于个人探索和接受自己的性别认同. 这项研究表明,对性别失调有潜在的治疗益处,但需要进一步的研究.
科学领域:
- 精神病学是一个精神病学.
- 心理学 心理学 心理学
- 神经科学是一个神经科学.
背景情况:
- 性别主题的迷幻体验,特别是用lysergic acid diethylamide (LSD) 的经验,有事报道,但缺乏系统的研究.
- 了解这些经验对于探索潜在的治疗应用至关重要.
研究的目的:
- 系统地探索以性别为主题的LSD体验.
- 了解这些经验的性质及其对性别认同的潜在治疗影响.
主要方法:
- 追溯观察性研究分析了来自"r/LSD" subreddit. 的帖子和评论.
- 对含有性别相关术语的帖子进行主题分析 (例如",性别"",跨性别"",跨").
主要成果:
- 在94个事中,47.9%的作者被认定为非cisgender,大多数报告增强了性别自我接受.
- 17.0%的人质疑性别,93.8%的人报告LSD澄清了他们的身份.
- 16.0%的人表示LSD影响了他们的过渡计划; 29.2%的cisgender作者发现LSD后持久的非cisgender身份.
结论:
- Lysergic acid diethylamide (LSD) 可能有助于探索和接受性别认同,这表明它可能在治疗性别失调症方面发挥作用.
- 临床试验必须在知情同意期间考虑潜在的LSD诱导的性别认同变化.
- 建议通过调查和前性研究进行进一步的研究,以验证这些发现.
相关概念视频
Hallucinogens and Psychedelics
294
Hallucinogens are psychoactive substances that profoundly alter perceptual experiences, generating unreal visual and sensory images. Often referred to as psychedelic drugs — a term derived from the Greek words "psyche" (mind) and "delos" (revealing) — these substances include marijuana and lysergic acid diethylamide (LSD), among others. These drugs vary in intensity and effects.
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains...
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains...
294
CNS Stimulants: Psychedelic Agents
256
Hallucinogens, also known as psychedelic drugs, are a class of substances known for their ability to alter perception, cognition, and emotions. Despite their profound effects on the mind, these drugs are non-addictive, setting them apart from many other abused substances. The mechanism of action of these drugs lies in their impact on the 5-HT2A receptor in the brain. Upon activation, this receptor couples to Gq-type G proteins, triggering a cascade that releases intracellular calcium. This...
256
Altered States of Awareness
508
Altered states of consciousness represent significant deviations from one's normal mental state. These deviations can range from subtle changes in awareness to profound transformations in perception, thought processes, and sensory experiences. Altered states of consciousness can be triggered by various factors, including drug use, meditation, hypnosis, illness, or even intense fatigue.
The ingestion of substances like stimulants or hallucinogens leads to chemical alterations in the brain...
The ingestion of substances like stimulants or hallucinogens leads to chemical alterations in the brain...
508
Drugs Affecting Neurotransmitter Synthesis
1.6K
Drugs affecting neurotransmitter synthesis can impact the adrenergic neuron and the synthesis of neurotransmitters. For example, α-methyltyrosine and carbidopa target specific enzymes involved in catecholamine synthesis. α-methyltyrosine inhibits the enzyme tyrosine hydroxylase, which converts tyrosine into dopamine. By blocking this enzyme, α-methyltyrosine reduces dopamine production and other catecholamines. Carbidopa, on the other hand, inhibits the enzyme dopa decarboxylase,...
1.6K
An Overview of Psychoactive Drugs
309
Psychoactive drugs impact brain function, influencing perception, mood, consciousness, cognition, and behavior. These substances are grouped based on their effects and the mechanisms by which they act.
Stimulants such as cocaine, amphetamines, and nicotine enhance brain activity, leading to increased alertness, attention, and energy. These drugs typically raise heart rate, blood pressure, and body temperature. While they can induce feelings of euphoria, their misuse can result in severe health...
Stimulants such as cocaine, amphetamines, and nicotine enhance brain activity, leading to increased alertness, attention, and energy. These drugs typically raise heart rate, blood pressure, and body temperature. While they can induce feelings of euphoria, their misuse can result in severe health...
309
Drugs Affecting Neurotransmitter Release or Uptake
1.2K
Certain drugs can affect how neurotransmitters called catecholamines, are released or taken back up in the adrenergic neuron. They can have different effects on the body's sympathetic transmission. Reserpine, a natural compound found in the Rauwolfia shrub, blocks a transporter called vesicular monoamine transporter (VMAT), which leads to a buildup of catecholamines in the cell and reduces sympathetic transmission. Another drug called guanethidine works in multiple ways, including blocking...
1.2K


