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Updated: Sep 19, 2025

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
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Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells

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辅助条件塑造了适应性免疫反应,通过NLRP3 / 介质素-1促进免疫耐受性

Thais Boccia1, Weikang Pan1, Victor Fattori2

  • 1Department of Surgery, Boston Children's Hospital - Harvard Medical School, Boston, MA, USA.

iScience
|June 18, 2025
PubMed
概括

重复施用,称为辅助条件 (AC),通过扩大髓质衍生抑制细胞 (MDSCs) 产生免疫抑制状态. 这一过程依赖于NLRP3和IL-1信号传递,延迟了全源移植的移植排斥,并为移植耐受性提供了潜在的标.

关键词:
免疫反应的免疫反应.免疫学 免疫学 免疫学

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