系统性免疫-炎症指数对非功能性 mitrale 吐患者的预后的影响 接受隔离性 mitrale 置换的患者
Busra Temel Yuksel1, Mehmet Isık2, Omer Tanyeli2
1Department of Cardiovascular Surgery, Şırnak State Hospital, Şırnak, Turkey.
Brazilian journal of cardiovascular surgery
|June 18, 2025
概括
手术前和手术后的免疫炎症指数 (SII) 和中性粒细胞与淋巴细胞比率 (NLR) 预测了 mitra 置换患者的早期死亡率. 更高的术后SII与更长的ICU停留时间相关,表明其预后价值.
科学领域:
- 心血管外科心血管外科
- 免疫学 免疫学 免疫学
- 预测生物标志物 预测生物标志物
背景情况:
- 非功能性额头吐需要额头置换 (MVR).
- 在MVR之后,早期预后和死亡率预测仍然是临床的关键挑战.
- 系统性免疫炎症指数 (SII) 和中性粒细胞与淋巴细胞比率 (NLR) 是新兴的炎症标志物.
研究的目的:
- 评估手术前和手术后SII和NLR的预测价值,以预测在接受隔离MVR的患者的早期预后.
- 评估这些炎症标志物与30天死亡率和重症监护室 (ICU) 住院的相关性.
主要方法:
- 在2015年至2021年期间,对176名接受隔离MVR的患者进行了回顾性分析.
- 从手术前和手术后早期的血液样本 (1日和4日) 计算SII,NLR和血小板与淋巴细胞比率 (PLR).
- 统计相关性分析与30天死亡率和ICU入院时间.
主要成果:
- 发现年龄,手术前的NLR,手术前的SII和术后的第4天NLR与30天死亡率之间存在显著的正相关性.
- 年龄与术前SII,术前NLR或术后4日NLR的组合是30天死亡率的显著预测因素.
- 术后4天SII值较高与更长的ICU入院时间有显著的相关性.
结论:
- 术前和术后4天的SII和NLR是预测30天预后的有价值指标,用于为非功能性 mitrale regurgitation 进行隔离 MVR 的患者.
- 术后4天SII升高可能预测长时间的ICU停留,有助于资源配置和患者管理.
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