HEY1CD44/EGFR/FAK

Yuhang Liu1, Hao Zhang1, Xinzeyu Yi1

  • 1Department of trauma and microorthopaedics, Zhongnan Hospital of Wuhan University, Wuhan, China.

概括

HEY1是一种关键的瘤基因,在骨髓瘤 (OS) 中过度表达. 沉默HEY1通过调节CD44介导EGFR-FAK通路来抑制OS细胞的增殖,为这种致命的癌症提供了潜在的治疗标.

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