在绝经前/绝经后妇女中,低骨矿物质密度的负担,趋势和预测
Jun Liao1, Yide Wang1, Reyla Turson1
1Department of Rehabilitation, The Fourth Clinical Medical College of Xinjiang Medical University, Urumqi, Xinjiang, China.
概括
低骨矿物质密度 (LBMD) 构成日益严重的全球健康威胁,绝经前和绝经后妇女的死亡率显著增加. 早期查和有针对性的预防对于解决这种未被充分认识到的负担至关重要.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 老年学是一门学科.
背景情况:
- 低骨矿物质密度 (LBMD) 是全球发病率和死亡率的主要因素,特别是在绝经后的妇女中.
- 在绝经前妇女中,LBMD的健康负担往往被低估.
- 了解LBMD的全球趋势和未来预测对于公共卫生战略至关重要.
研究的目的:
- 评估LBMD相关结果的全球负担和时间趋势.
- 预测到2035年LBMD的未来趋势.
- 为了突出LBMD负担在更年期前和更年期后妇女之间的差异.
主要方法:
- 在204个国家利用了2021年全球疾病负担研究 (1990-2021) 的数据.
- 提取了绝经前和绝经后妇女的发病率,死亡率和经残疾调整的寿命年 (DALY).
- 采用年龄标准化,不平等指数和贝叶斯马尔科夫链蒙特卡洛模型进行趋势预测.
主要成果:
- 从1990年到2021年,与LBMD相关的死亡率在绝经前妇女中增加了27.39%,在绝经后妇女中增加了138.73%.
- 2021年,绝经后妇女的年龄标准化死亡率是绝经前妇女的63.5倍.
- 未来的预测表明,到2035年,由于人口增长和老龄化,整体死亡率和DALY将增加,尽管年龄标准化率正在下降.
结论:
- 全球LBMD的绝对负担正在增加,尽管年龄标准化率正在下降.
- 针对性预防和早期查对于绝经后和未被认可的绝经前妇女都至关重要.
- 解决LBMD需要采取全面的方法来缓解其日益增长的全球影响.
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