皮肤上的阿波克林衍生眼病变:一系列的病变
Virali Dharmen Shah1, Allison B Resnik1, Daniel B Azzam1
1Department of Ophthalmology, Tufts University School of Medicine, Boston, Massachusetts, USA.
Orbit (Amsterdam, Netherlands)
|June 18, 2025
概括
眼汗腺瘤与阿波克林分化是罕见的,并且经常被误诊. 早期活检和详细的组织病理学对于准确诊断和有效管理这些独特的眼病变至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 皮肤病理学 皮肤病理学
- 在瘤学瘤学.
背景情况:
- 眼病变与阿波克林分化不常见,并且经常被误诊.
- 正确的诊断是具有挑战性的,因为各种表现,模仿良性或恶性疾病.
研究的目的:
- 描述罕见的眼瘤的临床和本病学特征与阿波克林分化.
- 突出免疫组织化学在区分这些病变中的作用.
主要方法:
- 对1,920个经过活检的汗腺病变进行了回顾性审查.
- 分析了七个独特的皮肤眼皮瘤与阿波克林分化.
- 组织病理学检查和免疫组织化学染色.
主要成果:
- 确诊的7例病例中,单侧眼的汗腺病变扩大.
- 标志性特征包括双层上皮质,断头分泌物和异性细胞质.
- 发现的病变包括:阿波克林细胞瘤,注射剂细胞瘤 (syringocystadenoma papilliferum),管状阿波克林腺瘤和阿波克林腺癌.
结论:
- 眼的汗腺病变与阿波克林分化需要仔细的体病理学评估,以准确诊断.
- 早期检测和活检对于适当的管理至关重要,特别是对于恶性病例.
- 手术切除是主要的治疗方式.
相关概念视频
Accessory Structures of the Skin: Sebaceous Glands
5.5K
A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
5.5K
Skin Diseases and Disorders
5.4K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.4K
Skin Cancer
5.2K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.2K
Microbiome of the Eye
67
The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
67
Acne Infection
94
Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
94
Cirrhosis I: Introduction
28
Cirrhosis is a chronic, irreversible liver disease characterized by the widespread replacement of healthy liver tissue with fibrotic scar tissue and the formation of regenerative nodules.Etiology of cirrhosisCirrhosis results from sustained liver injury that triggers progressive fibrosis and structural remodeling. The underlying causes are diverse, encompassing common and less frequent clinical conditions. Regardless of the origin, all causes lead to chronic inflammation, hepatocyte loss, and...
28


