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Updated: Sep 19, 2025

Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
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Satb1通过抑制IL-2表达来指导TH17细胞的分化

Maren Köhne1, Mehrnoush Hadaddzadeh Shakiba1, Lisa Schmidleithner1

  • 1Immunogenomics & Neurodegeneration, German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.

Cell reports
|June 18, 2025
PubMed
概括

特别的AT丰富的序列结合蛋白1 (Satb1) 是T辅助17 (TH17) 细胞发育的关键因素. Satb1通过抑制互白素-2信号来调节TH17的分化,为自身免疫性疾病提供了潜在的治疗标.

关键词:
CD4 (((+) T细胞分化的过程CP: 免疫学 免疫学欧洲电子商务管理局 (EEAE)在IL-2中,IL-2被认为是IL-2.在Satb1上,我们可以看到Satb1.T(H) 17 个细胞.自身免疫性疾病是一种自身免疫性疾病.大肠炎是一种大肠炎.这就是scRNA-seqq.一个单细胞的多OMIC.

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