与瘤相关的甘氨酸利用腺素受体2A信号来促进免疫逃避

Jing-Yan Cheng1, Hsiu-Hui Tsai1, Jung-Tung Hung1

  • 1Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital Linkou Medical Center, 15, Wenhua 1st Rd., Taoyuan, 333, Taiwan.

概括

环球H胺 (GHCer) 激活瘤中的腺素信号,抑制T细胞的反应. 这种葡萄糖脂促进调节性T细胞并增强其免疫抑制功能,突出了新的癌症治疗点.

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